Clinical 20% Niacinamide Treatment

serum · 20 ml · Skincare

Paula's Choice Clinical 20% Niacinamide Treatment is free of fragrance, essential oils, labelled fragrance allergens, drying alcohol, sulfates, silicones, parabens and MI / MCI, going by its full 26-ingredient list, with niacinamide, glycerin and vitamin C. List checked November 5, 2026.

The catch: none. It clears all 12 ingredient flags we check.

Fragrance-free
No essential oils
No labelled fragrance allergens
No drying alcohol
Sulfate-free
Silicone-free
Paraben-free
No MI/MCI

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Key ingredients in Clinical 20% Niacinamide Treatment

Niacinamide
Vitamin B3; helps with oil, redness, uneven tone and the barrier.
Glycerin
A classic humectant that keeps skin hydrated.
Vitamin C
An antioxidant that brightens and evens tone.
Panthenol (pro-vitamin B5)
Soothes and helps skin and hair hold moisture.
Allantoin
A soothing, softening ingredient.

Full ingredient list, decoded

26 ingredients, in label order (highest amount first; below about 1% the order is free).

1Water (Aqua/Eau)
2NiacinamideNiacinamide is a form of vitamin B3 used in skincare and haircare to help with oil,…
3Pentylene GlycolPentylene Glycol is a small, multi-tasking liquid that attracts water to the skin and…
4GlycerinGlycerin is a clear, thick, odorless liquid that pulls water into the skin and helps…
5Butylene GlycolButylene Glycol is a clear, odorless liquid that attracts and holds water. It is a…
6Acetyl Glucosamine
7Ascorbyl GlucosideA stable, water-soluble form of vitamin C that skin slowly converts to its active…
8Glycyrrhiza Glabra (Licorice) Root ExtractA plant extract made from the root of the licorice plant, Glycyrrhiza glabra. It is…
9Spiraea Ulmaria Extract
10Portulaca Oleracea Extract
11Camellia Japonica Flower Extract
12Epigallocatechin Gallate
13Boerhavia Diffusa Root Extract
14Camellia Sinensis Leaf ExtractA plant extract made from the leaves of the tea plant. Formulators use it mainly to add…
15AllantoinAllantoin is a white crystalline powder that soothes and softens skin and is widely…
16LecithinLecithin is a natural mix of fatty substances called phospholipids, taken from plant or…
17Pullulan
18PanthenolPanthenol is a form of vitamin B5 that the skin and hair convert to pantothenic acid.…
19SilicaSilica is a fine, white powder made of silicon and oxygen that mainly helps control…
20Xanthan GumXanthan Gum is a thickener and stabilizer made by fermenting sugar with a bacterium. It…
21Sclerotium GumSclerotium Gum is a thickening polymer made by fermenting a fungus. It gives creams and…
22PropanediolPropanediol is a clear liquid that draws water toward the skin. Its jobs are as a…
23Sodium PhytateA plant-derived salt that acts as a chelating agent, grabbing onto metal ions like…
24Sodium HydroxideSodium hydroxide is a strong alkali, also called caustic soda. In small amounts it…
25EthylhexylglycerinEthylhexylglycerin is a lab-made, skin-friendly ingredient that boosts the power of…
26PhenoxyethanolA synthetic preservative that helps stop bacteria, yeast and mold from growing in…

Source: Paula's Choice product page, www.paulaschoice.co.uk/niacinamide-treatment/m8030.html, retrieved November 5, 2026.

Every flag we check

Check	Result	Ingredients found
Fragrance	None listed	—
Essential oils	None listed	—
Labelled fragrance allergens	None listed	—
Drying alcohol	None listed	—
Sulfates	None listed	—
Silicones	None listed	—
Parabens	None listed	—
MI / MCI	None listed	—
Formaldehyde releasers	None listed	—
Mineral oil & petrolatum	None listed	—
Lanolin	None listed	—
Chemical UV filters	None listed	—

Frequently asked questions

Is Paula's Choice Clinical 20% Niacinamide Treatment fragrance-free?

Yes. Paula's Choice Clinical 20% Niacinamide Treatment lists no parfum or fragrance and no essential oils. Checked against its full ingredient list on November 5, 2026.

Does Paula's Choice Clinical 20% Niacinamide Treatment contain silicones, sulfates or parabens?

Silicones: none listed. Sulfates: none listed. Parabens: none listed.

Which ingredient rules does Paula's Choice Clinical 20% Niacinamide Treatment pass?

Its full list passes our ingredient rules for sensitive skin, eczema-prone skin, contact dermatitis and perfume allergy. Key ingredients: Niacinamide, Glycerin, Vitamin C and Panthenol (pro-vitamin B5).